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CtRT′－CtRT－′，E＝10[－1\u002Fslope]－1，Ct值是指荧光信号达到阈值时的循环数，RT表示反转录，RT－表示非反转录。本发明具有过程简单、易操作、一次性可进行大量样品检测、结果直观、敏感性高、特异性强、重复性好等优点。","东北农业大学","2008.04.30#公开;2008.06.25#实质审查的生效;2010.01.06#授权","CN200710144570.8","C12Q1\u002F68","姜毓君;相丽;闫冰;毕宇涵;曲妍妍;赵凤;刘伟",[],[],{"resultType":1432,"id":1514,"title":1515,"abstract":1516,"orgName":1506,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1517,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1518,"ipc":1519,"inventors":1520,"tags":1521,"tagNames":1522},"gpi_00501","一种同时检测原料乳中多种致病菌的方法及检测试剂盒","一种同时检测原料乳中多种致病菌的方法及检测试剂盒，它涉及了一种检测原料乳中细菌的方法及检测试剂盒。本发明解决了现有检测原料乳中致病菌的方法中存在不能同时检测多种致病菌、耗时长、费用高或不适用于检测牛乳的问题。本发明同时检测原料乳中多种致病菌的方法按照如下步骤进行：一、将待检测的原料乳去除脂肪；二、将步骤一保温后的样品过滤；三、收集洗脱液；四、进行多重PCR并对凝胶成像系统进行分析；即得到检测结果。本发明的试剂盒由Taq酶溶液、多重PCR反应液、阴性对照液和阳性对照液组成。本发明的方法具有耗时短、费用低、适用于检测牛乳和检测结果准确的优点。本发明的试剂盒使用方便。","2009.03.18#公开;2009.05.13#实质审查的生效;2011.03.09#著录事项变更;2011.07.27#授权","CN200810137442.5","C12Q1\u002F68;C12Q1\u002F04","姜毓君;吕琦;赵凤;刘伟;韩希妍;毕宇涵;王明娜;张光辉;相丽;闫冰",[],[],{"resultType":1432,"id":1524,"title":1525,"abstract":1526,"orgName":1452,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1527,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1528,"ipc":1529,"inventors":1530,"tags":1531,"tagNames":1532},"gpi_01534","一种基于形状记忆聚合物的可充气展开天线反射面及其反射表面片、蒙皮的制作方法","一种基于形状记忆聚合物的可充气展开天线反射面及其反射表面片、蒙皮的制作方法，涉及一种天线反射面及其反射表面片、蒙皮的制作方法，它解决了现有的可展开固体表面天线反射面折叠不方便的问题。它由反射表面体、第一环向气囊、第二环向气囊、径向气囊和蒙皮组成，在反射表面体的凸抛物面的上边缘及下边缘处分别固定连接有第一环向气囊和第二环向气囊，反射表面体的凸抛物面上均匀设置有圆周方向排列的N个径向气囊，在反射表面体的凸抛物面上覆盖有蒙皮；所述的反射表面片使用形状记忆聚合物材料涂敷纤维增强材料上；所述的蒙皮将形状记忆聚合物材料涂敷在柔性材料上。本发明所述的天线反射面能够进行方便的收缩及展开，用于航天通讯。","2010.10.06#公开;2010.11.24#实质审查的生效;2013.01.09#授权","CN201010180800.8","H01Q15\u002F16","冷劲松;刘彦菊;兰鑫;阳鹏",[],[],{"resultType":1432,"id":1534,"title":1535,"abstract":1536,"orgName":1452,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1537,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1538,"ipc":1539,"inventors":1530,"tags":1540,"tagNames":1541},"gpi_01520","一种基于形状记忆聚合物的可展开天线反射面及其骨架结构的制作方法","一种基于形状记忆聚合物的可展开天线反射面及其反射表面片的制作方法，涉及一种可展开天线反射面及反射表面片的制作方法。解决了现有的航天用可展开天线重量大、体积大、结构复杂并且存在展开和收缩不平稳的问题，可展开天线由环向动力件、环向加强件、径向加强件和反射膜拼接组成。反射表面片的制作方法如下：一、设计模具；步骤二、配制形状记忆聚合物材料；三、使用形状记忆聚合物材料涂敷纤维增强材料；四、形成未固化的纤维增强形状记忆聚合物毛坯；五、将闭合模具放置在加热箱内加热；六、脱模得到以纤维增强形状记忆聚合物为材料的骨架结构。本发明可作为航天领域的可展开天线反射面。","2010.09.29#公开;2010.11.17#实质审查的生效;2013.03.06#授权","CN201010180826.2","H01Q15\u002F16;H01Q1\u002F28",[],[],{"resultType":1432,"id":1543,"title":1544,"abstract":1545,"orgName":1546,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1547,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1548,"ipc":1549,"inventors":1550,"tags":1551,"tagNames":1552},"gpi_01793","一种建立急性多型性卟啉病转基因小鼠模型的方法","本发明提供了一种建立急性多型性卟啉病转基因小鼠模型的方法。本发明首先构建一线性转基因序列，利用构建的基因序列产生F0代转基因小鼠，该小鼠基因组中整合有外源性ALAS-E表达序列，将获得的阳性转基因小鼠与正常小鼠杂交，获得子代。本发明能够自发产生一系列典型的急性多型性卟啉病的生化、病理和临床特征，并首次出现ALA高而血红素不低的状态，完善了急性多型性卟啉病的病因，可作为急性多型性卟啉病动物模型用于急性卟啉病发病机制研究。","哈尔滨医科大学","2011.01.12#公开;2011.03.09#实质审查的生效;2013.01.09#授权","CN200910217442.0","C12N15\u002F52;C12N15\u002F89;C12N15\u002F90;C12Q1\u002F68;C12Q1\u002F25;A01K67\u002F027","高旭;周凌云;惠洋;马宁;彭亚会",[],[],{"resultType":1432,"id":1554,"title":1555,"abstract":1556,"orgName":1557,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1558,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1559,"ipc":1560,"inventors":1561,"tags":1562,"tagNames":1563},"gpi_01605","一种用于抗辐射的复合多糖","本发明公开了一种用于抗辐射的复合多糖，其有效成分为香菇多糖、姬松茸多糖、茯苓多糖，该复合多糖不仅能够明显地提高小鼠免疫力，而且还能增加对经γ射线照射后的小鼠的白细胞数、骨髓细胞DNA含量，具有更强的抗辐射效果。特别适用于肿瘤疾病放、化疗或肿瘤病术后的辅助治疗。","齐齐哈尔医学院","2010.11.10#公开;2010.12.22#实质审查的生效;2012.02.22#授权","CN201010243779.1","A61K31\u002F716;A61K31\u002F715;A61P17\u002F16;A61P39\u002F00;A61P37\u002F04","刘吉成;韩翠艳",[],[],{"resultType":1432,"id":1565,"title":1566,"abstract":1567,"orgName":1568,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1569,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1570,"ipc":1571,"inventors":1572,"tags":1573,"tagNames":1574},"gpi_01336","一种自动测试CAN总线控制模块的I\u002FO引脚的系统和方法","本发明公开了一种自动测试CAN总线控制模块的I\u002FO引脚的系统和方法，所述的系统包括配置单元、输入单元、输出检测单元和比较单元；所述的方法包括：步骤1，配置CAN总线控制模块的I\u002FO引脚的控制逻辑；步骤2，所述I\u002FO引脚输入信号；步骤3，检测所述CAN总线控制模块的输出信号；步骤4，从所述配置单元根据所述控制逻辑查找与所述输入信号对应的预定输出信号，并将所述预定输出信号与所述输出信号比较，如果两者相同则转至步骤5，如果两者不相同则转至步骤6；步骤5，输出该I\u002FO引脚的测试正确的信息，转至步骤7；步骤6，输出测试错误；步骤7，测试流程结束。本发明所述的系统和方法实现了对CAN模块进行全自动标准化测试。","哈尔滨威帝电子股份有限公司;哈尔滨工业大学","2010.07.14#公开;2010.09.15#实质审查的生效;2012.05.23#授权","CN200910001571.6","H04L12\u002F26;G05B23\u002F02;H04L12\u002F24","佟为明;林景波;卢雷;李方;陈振华;白哲松;吴鹏程",[],[],{"resultType":1432,"id":1576,"title":1577,"abstract":1578,"orgName":1452,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1579,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1580,"ipc":1529,"inventors":1581,"tags":1582,"tagNames":1583},"gpi_01582","可变形天线反射面","一种可变形天线反射面，它涉及一种天线反射面。本发明的目的是解决目前反射面天线无法满足复杂多变的空间环境，且在空间中不能对其进行在轨热变形控制和在轨振动控制导致在轨反射面天线精度降低及目前的空间天线不能结构变形无法满足各种空间要求的问题。所述驱动器包括端盖、驱动轴、壳体、工作线圈或导线和驱动功能材料体，所述端盖装在壳体上，所述驱动轴为十字形，所述驱动轴的一端与端盖连接，与其相对的一端与驱动功能材料体连接，另外两端与壳体的侧壁接触，驱动轴可沿壳体轴向滑动，工作线圈或导线设在驱动轴与壳体之间且位于驱动功能材料体的外部。本发明用于实现航天器天线在轨热变形的控制、振动控制和反射面变形。","2010.10.27#公开;2010.12.08#实质审查的生效;2012.12.19#授权","CN201010213907.8","冷劲松;刘彦菊;张蕊瑞;兰鑫",[],[],{"resultType":1432,"id":1585,"title":1586,"abstract":1587,"orgName":1452,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1588,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1589,"ipc":1590,"inventors":1591,"tags":1592,"tagNames":1593},"gpi_00446","基于光功率精确分离的纵向塞曼激光器稳频方法与装置","本发明属于激光应用技术领域，本发明的方法包括以下步骤：开启并预热置于纵向磁场中的激光管，利用四分之一波片和偏振分光器初步分离激光管出射的左、右旋圆偏振光得到两正交线偏振光；利用低漂移高频光电探测器将线偏振光转变为电信号并测出电信号中直流和交流分量的幅值，从而精确分离并测得两圆偏振光的光功率PL和PR；调整缠绕在激光管上的电热器件的电流值，改变激光管温度和谐振腔长，使光功率差PL－PR为零，两偏振光频率都得到稳定；本发明的装置包括用于获得光功率直流分量和交流分量的光功率精确分离检测电路；本发明的特点是利用低漂移高频光电探测器可同时测出线偏振光中混叠的两种不同频率激光的光功率，从而提高稳频激光器的频率稳定度。","2009.01.21#公开;2009.03.11#实质审查的生效;2010.01.27#授权","CN200810137081.4","H01S3\u002F137","谭久彬;胡鹏程;付海金;杨宏兴",[],[],{"resultType":1432,"id":1595,"title":1596,"abstract":1597,"orgName":1452,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1598,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1599,"ipc":1600,"inventors":1601,"tags":1602,"tagNames":1603},"gpi_00521","基于时域处理联合信道估计的正交频分复用系统","基于时域处理联合信道估计的正交频分复用系统，涉及移动通信技术领域。它解决了现有正交频分复用系统为减小峰均功率比使信号产生失真，影响系统性能的问题。它的步骤为：发射机：将经过IFFT变换后的时域信号进行线性滤波插值处理以减小峰均功率比，后经插入循环前缀和并\u002F串转换处理通过发射信道发射；接收机：将接收信号进行串\u002F并转换和线性逆变换获得两路并行的时域接收信号序列，将一路去除循环前缀后进行FFT变换得到并行的频域信号序列D′(n)；将另一路进行信道估计获得信道冲激响应，然后进行FFT变换得到并行的信道频率响应序列；将D′(n)和进行迫零均衡、并\u002F串转换、解映射和解调后得到比特信号。本发明适用于现有的OFDM系统。","2009.03.25#公开;2009.05.20#实质审查的生效;2011.06.22#授权","CN200810137497.6","H04L27\u002F26;H04L25\u002F03","贾敏;顾学迈;郭庆",[],[],{"resultType":1432,"id":1605,"title":1606,"abstract":1607,"orgName":1608,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1609,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1610,"ipc":1611,"inventors":1612,"tags":1613,"tagNames":1614},"gpi_00124","多靶点miRNA反义核苷酸技术","多靶点miRNA反义核苷酸技术，本发明涉及一种反义核苷酸技术。他是为了解决现有沉默miRNAs的方法存在靶向性单一，作用效力差的问题。多靶点miRNA反义核苷酸技术通过以下方法实现：一、通过基因芯片筛选或文献提供，找到可调节关键基因即致病基因的miRNA；二、将多条反义核苷酸设计到一个能同时沉默多个靶miRNAs的单条核苷酸序列中，即实现多靶点miRNA反义核苷酸技术。本发明可以作为一种简单而直接的方法，可对其它包含多种miRNA及多种基因的生物过程进行研究。CAMO方法与现有方法相比较其最大优势在于，可以使一个药物分子调节多个靶向基因，作用效果更加显著，解决了现有方法靶向性单一，作用效力差的问题。","哈尔滨医科大学;王志国","2008.02.13#公开;2008.04.09#实质审查的生效;2011.12.07#授权","CN200710072024.8","C12N15\u002F11;C07H21\u002F02;A61K31\u002F7088","杨宝峰;王志国;吕延杰;白云龙;初文峰",[],[],{"resultType":1432,"id":1616,"title":1617,"abstract":1618,"orgName":1452,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1619,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1620,"ipc":1621,"inventors":1622,"tags":1623,"tagNames":1624},"gpi_00922","大气低温等离子体化学修整金刚石刀具表面缺陷的方法","大气低温等离子体化学修整金刚石刀具表面缺陷的方法，属于大气低温等离子体化学修整金刚石刀具表面缺陷的方法。本发明的目的是为了解决目前金刚石刀具采用机械式研磨进行加工之后，刀具研磨表面及刃口存在的微观缺陷无法去除，从而影响到金刚石刀具的切削性能和使用寿命的问题。本方法为向等离子体发生器的阴极和阳极之间通入等离子体气体和反应气体的混合物，并在阴极和阳极上施加射频功率信号，然后在两个电极之间产生等离子体放电，将研磨完成的金刚石刀具置于等离子体放电区域之内加工10－30分钟后取出，即可实现对刀具的修整，电极的内部空腔通入循环冷却水。本发明用作对金刚石刀具表面微观缺陷的去除。","2009.12.09#公开;2010.02.03#实质审查的生效;2011.01.05#授权","CN200910072404.0","B23K10\u002F00;H05H1\u002F46","王波;金会良;张彦富;王景贺",[],[],{"resultType":1432,"id":1626,"title":1627,"abstract":1628,"orgName":1546,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1629,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1630,"ipc":1631,"inventors":1632,"tags":1633,"tagNames":1634},"gpi_00035","挂金灯甾类化合物的提取和应用及含挂金灯甾类化合物的药物组合物","挂金灯甾类化合物的提取和应用及含挂金灯甾类化合物的药物组合物，它涉及一种药物成分的提取和应用及含该药物成分的药物组合物。挂金灯甾类化合物用于治疗高血脂和糖尿病。提取方法：(一)煎煮；(二)离心；(三)超滤、浓缩，即得到含有挂金灯甾类化合物的浸膏。药物组合物可按质量百分比由65％～75％的挂金灯甾类化合物、15％～25％的山楂黄酮和5％～10％的大黄制成。药物组合物也可按质量百分比由55％～65％的挂金灯甾类化合物、32％～40％的姜黄素和3％～5％的刺五加皂苷制成。药物组合物还可按质量百分比由50％的挂金灯甾类化合物、30％的苦参碱和20％的苦瓜皂苷制成。挂金灯甾类化合物可用于治疗高血脂和糖尿病，有效率达100％。","2007.06.27#公开;2007.08.22#实质审查的生效;2010.02.10#授权","CN200610151201.7","A61K36\u002F81;A61K36\u002F708;A61P3\u002F06;A61P3\u002F10;A61K31\u002F56;A61K31\u002F352;A61K31\u002F122;A61K125\u002F00;A61K131\u002F00","杨宝峰;潘振伟;李国玉;方志伟;吕延杰;初文峰",[],[],{"resultType":1432,"id":1636,"title":1637,"abstract":1638,"orgName":1473,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1639,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1640,"ipc":1641,"inventors":1642,"tags":1643,"tagNames":1644},"gpi_00703","木豆叶中木豆芪酸及球松素在制备抗疱疹病毒药物中的应用","本发明涉及了木豆叶中木豆芪酸及球松素在制备抗疱疹病毒药物中的应用。包括木豆叶中木豆芪酸及球松素的提取方法和木豆叶中木豆芪酸及球松素在治疗疱疹病毒方面的新用途。木豆叶中木豆芪酸及球松素加入不同的赋形剂后可加工成任何一种药剂学上所说的剂型。木豆叶中木豆芪酸及球松素具有毒副作用小，疗效确切，安全可靠等特点。木豆资源丰富，采集方便，提取工艺简单，便于工业化生产。","2009.07.22#公开;2009.11.04#实质审查的生效;2011.01.05#授权","CN200910071471.0","A61K31\u002F192;A61K31\u002F352;C07C65\u002F24;C07D311\u002F32;A61P31\u002F22;A61K36\u002F48;A61K127\u002F00","付玉杰;祖元刚;吴楠;孔羽;刘威;华欣",[],[],{"resultType":1432,"id":1646,"title":1647,"abstract":1648,"orgName":1473,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1649,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1650,"ipc":1651,"inventors":1652,"tags":1653,"tagNames":1654},"gpi_00704","木豆叶提取物及其单体成分在制备抗革兰氏阳性菌药物中的应用","本发明公开了木豆叶提取物及其单体成分在制备抗革兰氏阳性菌药物中的应用。它涉及以木豆叶为原料按常规方法提取的乙醇粗提物，氯仿，乙酸乙酯，石油醚，正丁醇的萃取物和单体成分木豆芪酸、木豆内酯、球松素、牡荆苷、异牡荆苷的特异性抗革兰氏阳性菌活性用途。本发明具有易于制作，价格低廉，作用效果好的特点。可用于治疗由金黄色葡萄球菌引起的小儿肺炎，上呼吸道感染和由奶、肉、蛋、鱼及其制品，剩饭、油煎蛋、糯米糕及凉粉等引起的食物中毒。","2009.07.22#公开;2009.11.04#实质审查的生效;2010.12.29#授权","CN200910071467.4","A61K36\u002F48;A61P31\u002F04;A61K127\u002F00","付玉杰;祖元刚;刘晓蕾;刘威;孔羽;顾成波;吴楠",[],[],{"resultType":1432,"id":1656,"title":1657,"abstract":1658,"orgName":1473,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1659,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1660,"ipc":1661,"inventors":1662,"tags":1663,"tagNames":1664},"gpi_00848","木豆叶超临界提取物及木豆芪酸在制备抗肿瘤药物中的应用","本发明涉及了从木豆叶超临界提取物及其主要成分-木豆芪酸(包括木豆芪酸I－VI)在抗肿瘤方面的新用途。木豆芪酸加入不同的赋形剂后可加工成任何一种药剂学上所说的剂型。木豆叶中超临界提取物及木豆芪酸(包括木豆芪酸I－VI)具有毒副作用小，疗效确切，安全可靠等特点。木豆资源丰富，采集方便，提取工艺简单，便于工业化生产。","2009.11.04#公开;2009.12.30#实质审查的生效;2011.02.02#授权","CN200910072218.7","A61K36\u002F48;A61K31\u002F192;A61P35\u002F00;A61K127\u002F00","付玉杰;祖元刚;刘霞;吴楠;孔羽;罗猛;顾成波;彭霄",[],[],{"resultType":1432,"id":1666,"title":1667,"abstract":1668,"orgName":1669,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1670,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1671,"ipc":1672,"inventors":1673,"tags":1674,"tagNames":1675},"gpi_00259","猪传染性胃肠炎华毒弱毒疫苗株及其应用","本发明公开了一种猪传染性胃肠炎华毒(H)弱毒疫苗株(Transmissible gastroenteritis virus)及其应用。本发明弱毒疫苗株的微生物保藏号是：CCTCC－V200609。本发明TGEV弱毒株安全性好，对于猪传染性胃肠炎(TGE)病毒具有良好的免疫保护率。本发明弱毒株可应用于制备成诊断猪传染性胃肠炎的诊断试剂，还可应用于制备成防治猪传染性胃肠炎的单苗或联苗(活或灭活疫苗)等。","中国农业科学院哈尔滨兽医研究所","2008.08.06#公开;2008.10.01#实质审查的生效;2010.08.18#授权","CN200710003045.4","C12N7\u002F00;C12N15\u002F50;A61K39\u002F225;A61K35\u002F76;A61P31\u002F12;G01N33\u002F569","冯力;王承宝;时洪艳;陈建飞;佟有恩;王明;马思奇",[],[],{"resultType":1432,"id":1677,"title":1678,"abstract":1679,"orgName":1669,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1680,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1681,"ipc":1682,"inventors":1683,"tags":1684,"tagNames":1685},"gpi_00118","猪流行性腹泻病毒弱毒疫苗株及其应用","本发明公开了猪流行性腹泻病毒弱毒疫苗株及其应片。本发明弱毒疫苗株的微生物保藏号是：CCTCC－V200608。本发明弱毒疫苗株安全性好，对于猪流行性腹泻病毒具有良好的免疫保护率。本发明弱毒株可应用于可应用于制备成防治猪流行性腹泻病毒的单苗或联苗(活或灭活疫苗)等，也可制备成诊断猪流行性腹泻病毒的诊断试剂。","2008.02.06#公开;2008.04.02#实质审查的生效;2010.07.14#授权","CN200710003047.3","C12N7\u002F00;C12N15\u002F33;A61K39\u002F12;A61K35\u002F76;A61P1\u002F12;G01N33\u002F569","冯力;陈建飞;时洪艳;佟有恩;孙东波",[],[],{"resultType":1432,"id":1687,"title":1688,"abstract":1689,"orgName":1546,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1690,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1691,"ipc":1692,"inventors":1693,"tags":1694,"tagNames":1695},"gpi_00798","用于检测样本中mircoRNAs含量的核苷酸序列及检测方法","本发明提供用于检测样本中mircoRNA含量的核苷酸序列及试剂盒，以及以核酸碱基配对识别互补结合为基础，经银染增强的纳米金标记探针的miRNAs检测方法，该方法简单易行，无需放射性标记、荧光等昂贵设备就可获得高灵敏度，高特异度的检测信号。","2009.09.23#公开;2009.11.11#实质审查的生效;2012.05.30#授权","CN200910135756.6","C12Q1\u002F68;C12N15\u002F11;G01N33\u002F53","杨宝峰;王志国;吕延杰;张荣;初文峰",[],[],{"resultType":1432,"id":1697,"title":1698,"abstract":1699,"orgName":1669,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1700,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1701,"ipc":1702,"inventors":1703,"tags":1704,"tagNames":1705},"gpi_01865","腺病毒\u002F甲病毒复制子嵌合载体猪瘟疫苗及其应用","本发明公开了腺病毒\u002F甲病毒复制子嵌合载体猪瘟疫苗及其应用。本发明利用基因转移能力极强的腺病毒来递送表达猪瘟病毒E2蛋白的甲病毒复制子载体，构建了高效表达CSFV E2蛋白的腺病毒\u002F甲病毒复制子嵌合载体疫苗，其微生物保藏号是：CGMCC No.4146；本发明嵌合载体疫苗通过腺病毒载体递送表达CSFV E2蛋白的甲病毒复制子载体疫苗，既能发挥腺病毒载体的高效转移外源基因的能力，又能发挥甲病毒复制子载体自我复制后高效表达外源基因及其诱导强大细胞免疫应答的优势，大大增强了疫苗的免疫效力，免疫剂量也大大减少。本发明嵌合载体疫苗在猪体上能诱导高水平的免疫反应，可对致死性猪瘟病毒强毒的攻击提供完全的保护。","2011.02.09#公开;2011.04.27#实质审查的生效;2012.06.27#授权","CN201010297576.0","A61K48\u002F00;A61K39\u002F187;C12N15\u002F40;C12N15\u002F861;A61P31\u002F14","仇华吉;孙元;李娜;李宏宇",[],[],{"resultType":1432,"id":1707,"title":1708,"abstract":1709,"orgName":1710,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1711,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1712,"ipc":1713,"inventors":1714,"tags":1715,"tagNames":1716},"gpi_00414","虫草多糖含片及其制备方法","本发明涉及一种虫草多糖含片及其制备方法，其中：虫草多糖提取物50％－70％、罗汉果提取物5％－15％、绿茶提取物2％－10％，复合填充剂20％－30％，其制备方法为，取虫草多糖提取物、罗汉果提取物、绿茶提取物分别过100目筛，加入复合填充剂后，混合，将混合均匀的药粉置槽型混合机中，然后加入配好的润湿剂，搅拌，之后将混合充分的软料投入摇摆式颗粒机中过尼龙筛造粒，再把颗粒入真空干燥机中进行干燥，整粒，混匀后用压片机器压片。该发明组方合理、活性成分均衡，风味独特，适合一种适合大多数人服用的保健食品。","黑龙江新医圣制药有限责任公司;上海交通大学","2008.12.31#公开;2009.02.25#实质审查的生效;2011.09.21#授权","CN200810036761.7","A61K36\u002F82;A61K9\u002F20;A61P11\u002F04;A61P37\u002F02","汪新;周选围",[],[],{"resultType":1432,"id":1718,"title":1719,"abstract":1720,"orgName":1452,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1721,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1722,"ipc":1723,"inventors":1724,"tags":1725,"tagNames":1726},"gpi_01021","被动式毫米波成像系统","被动式毫米波成像系统，它涉及一种毫米波成像系统。它解决了现有毫米波成像系统通过焦面阵成像的方式导致的系统成像时间长、实时性差，以及获得的图像分辨率低的问题。它的金属反射板将待测目标辐射出的电磁波反射至并经介质透镜汇聚至接收天线上，接收到的信号先后经毫米波段高增益低噪声放大器、高灵敏度平方律检波器、低通滤波器滤波和低频放大器处理后由数字采集电路进行采集，采集到信号传输至计算机中进行成像处理。本发明适用于安检领域。","2010.02.10#公开;2010.04.14#实质审查的生效;2011.09.07#授权","CN200910072804.1","G01S13\u002F89;G01S7\u002F40","邱景辉;陈立甲;王楠楠;庄重;李高飞",[],[],{"resultType":1432,"id":1728,"title":1729,"abstract":1730,"orgName":1669,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1731,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1732,"ipc":1733,"inventors":1734,"tags":1735,"tagNames":1736},"gpi_01004","轮状病毒基因重配毒株及其构建方法和应用","本发明公开了一株轮状病毒基因重配毒株及其构建方法和应用，属于轮状病毒的诊断和防制领域。本发明轮状病毒基因重配毒株以羊轮状病毒弱毒株的VP1、VP2、VP3、VP4、NSP1、VP6、NSP2、NSP3、NSP4和NSP5基因为该重配毒株的基因骨架并重配了牛轮状病毒株的VP7基因节段，其微生物保藏号是：CGMCC No.3102。本发明重配毒株R191与LLR－85毒株联合应用可构成能够涵盖牛轮状病毒主要血清型G6和G10型的二价减毒活疫苗。在新生犊牛体内对两株疫苗候选毒株进行了免疫原性和病毒释放的评价，结果显示，疫苗候选毒株在新生犊牛体内具有良好的免疫原性和很低的病毒释放率。","2010.01.27#公开;2010.03.24#实质审查的生效;2011.11.09#授权","CN200910161345.4","C12N7\u002F00;C12N7\u002F01;G01N33\u002F543;A61K39\u002F15;A61K39\u002F295;A61P31\u002F14;A61P1\u002F12;C12Q1\u002F70;C12Q1\u002F68;C12R1\u002F93","于力;常继涛",[],[],{"resultType":1432,"id":1738,"title":1739,"abstract":1740,"orgName":1669,"province":1437,"date":1474,"trl":10,"transferMode":10,"keywords":10,"industry":10,"patentType":1439,"legalStatus":1741,"isOpenLicense":1441,"isRevitalized":1442,"techMaturity":10,"starRating":10,"licenseFeeText":10,"patentNo":1742,"ipc":1743,"inventors":1744,"tags":1745,"tagNames":1746},"gpi_01775","鸡传染性法氏囊病病毒重组弱毒疫苗株及其应用","本发明公开了鸡传染性法氏囊病病毒重组弱毒疫苗株及其应用。本发明克隆了流行超强毒株HLJ-0504的主要保护性抗原基因VP2，将其核苷酸进行突变修饰，然后将其替换IBDV弱毒株Gt基因组的相应区段，构建IBDV重组基因组的感染性克隆，利用IBDV反向遗传操作系统，拯救并鉴定了重组弱毒疫苗株，其微生物保藏号是：CGMCC No.3749；本发明重组弱毒疫苗株具有良好的复制性、遗传稳定性和安全性。在免疫效果上，本发明弱毒疫苗株和中等毒力疫苗相当，优于弱毒疫苗株。在生物安全性上，优于中等毒力疫苗。本发明重组弱毒疫苗株具备作为疫苗株的高效、低毒的特点，是良好的疫苗候选毒株，可用于鸡传染性法氏囊病的防控。","2011.01.05#公开;2011.04.20#实质审查的生效;2011.12.21#授权","CN201010215328.7","C12N7\u002F01;C12N15\u002F40;A61K39\u002F12;A61P31\u002F14;G01N33\u002F569;C12R1\u002F93","王笑梅;祁小乐;高玉龙;高宏雷;秦立廷;王永强;高立",[],[],{"list":1748,"total":1759,"page":475,"pageSize":475,"totalPages":1759},[1749],{"id":1750,"name":1751,"orgName":1752,"school":10,"gender":10,"title":10,"degree":10,"honor":1753,"position":1754,"researchDirection":1755,"intro":10,"province":10,"completeness":180,"avatarAuthorized":1441,"sourceUrl":1756,"nameValid":1442,"tags":1757,"tagNames":1758},"cmv7rn1er000jddmmau8qulzd","应汉杰","苏州大学","ACADEMICIAN","苏州大学校长","生物制造与酶催化方向专家","chaingraph:\u002F\u002F应汉杰",[],[],35346]