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后将得到的正辛酰氯与2-巯基吡啶在碱性条件下缩合反应生成式(V)表示的物质，然后将式(V)表示的物质在碱性条件下反应生成式(VI)表示的物质；c)将步骤a)得到的物质和步骤b)得到的物质在路易斯酸催化条件下反应生成式(VII)表示的物质，然后与路易斯酸反应。各式中的标号和说明书中含义相同。","重庆植恩药业有限公司;四川大学","2026-10-12T00:54:35.109Z","PCT发明","2011.01.05#公开;2011.05.04#实质审查的生效;2013.10.23#授权;2021.05.07#专利权人的姓名或者名称、地址的变更","CN200880126547.9","C07D305\u002F12","秦勇;邓祥林;周旋;于国锋;王科;宋颢;王晓琳;黄山",[],[],{"resultType":1085,"id":1189,"title":1190,"abstract":1191,"orgName":1192,"province":1090,"date":1180,"trl":13,"transferMode":13,"keywords":13,"industry":13,"patentType":1092,"legalStatus":1193,"isOpenLicense":1094,"isRevitalized":1095,"techMaturity":13,"starRating":13,"licenseFeeText":13,"patentNo":1194,"ipc":1195,"inventors":1196,"tags":1197,"tagNames":1198},"gpi_00587","GSM系统空帧检测方法","本发明请求保护一种GSM系统空帧检测方法，涉及移动通信技术领域，本方法利用移动台接收数据的训练序列Midamble左右的数据块平均功率比值进行第一次判断，并根据有用信号受快衰落信道影响而表现出功率快速波动的特性，再次利用Midamble左右的数据块平均功率比值对判断结果进行第二次判断确认，以准确判断所接收的突发数据是有用帧还是在空帧中。本发明适用于快衰落信道条件下，信道冲激响应较难准确估计的情况。","重庆邮电大学","2009.05.20#公开;2009.07.15#实质审查的生效;2016.06.01#授权","CN200810237145.8","H04B1\u002F707;H04B7\u002F26;H04W52\u002F24","向浏欣;魏进民;曾垂省",[],[],{"resultType":1085,"id":1200,"title":1201,"abstract":1202,"orgName":1203,"province":1090,"date":1180,"trl":13,"transferMode":13,"keywords":13,"industry":13,"patentType":1092,"legalStatus":1204,"isOpenLicense":1094,"isRevitalized":1095,"techMaturity":13,"starRating":13,"licenseFeeText":13,"patentNo":1205,"ipc":1206,"inventors":1207,"tags":1208,"tagNames":1209},"gpi_00271","一种心肌缺血治疗仪","本发明提供一种心肌缺血治疗仪，由电源电路、调制波发生电路、调制波整形电路、调幅电路、恒流源电路、刺激电极、CPLD载波发生电路、载波整形电路、输出强度控制电路和单片机组合而成。它具有无创性、无痛感电刺激、克服机体的适应性等特点，使患者在舒适感觉中接受治疗。使用本发明治疗仪通过经皮脊髓电刺激和小脑顶核电刺激可辅助治疗心肌缺血。本发明治疗仪是将低频慢变化节奏的随机信号，以脉冲幅度调制的方式，调制在具有特定频谱结构的中频载波信号上，通过体表电极以电流的形式从体外将低频电流加载到人体的脊髓和小脑顶核，通过改善冠脉血流、降低心肌耗氧量、控制疼痛和神经源性神经保护作用达到治疗心肌缺血的治疗作用。","重庆大学;重庆海坤医用仪器有限公司","2008.08.13#公开;2008.10.08#实质审查的生效;2011.08.31#授权","CN200810069283.X","A61N1\u002F36","田学隆;朱冰莲;董为伟;陈运贞;翁振兴",[],[],{"resultType":1085,"id":1211,"title":1212,"abstract":1213,"orgName":1214,"province":1090,"date":1180,"trl":13,"transferMode":13,"keywords":13,"industry":13,"patentType":1092,"legalStatus":1215,"isOpenLicense":1094,"isRevitalized":1095,"techMaturity":13,"starRating":13,"licenseFeeText":13,"patentNo":1216,"ipc":1217,"inventors":1218,"tags":1219,"tagNames":1220},"gpi_01071","一种数字化变电站电子式互感器的故障诊断方法","一种数字化变电站电子式互感器的故障诊断方法，它通过采集电子式互感器安装处三相电压、三相电流共六条通道互感器的输出数据，然后采用Bior3.1小波基函数对六条通道的输出数据分别进行四层小波变换，并逐层获取模极大值点。将采集并计算得到的模极大值与设定的各层阈值比较，大于阈值的保存下来，并采用多尺度模极大值综合处理方法获取信号奇异时刻。对比六条通道信号奇异时刻，并采用多通道信息融合处理方法，识别出现故障的通道对应的电子式互感器。可实时给出各通道电子式互感器的运行状况，同时对于异常状态的电子式互感器给出报警信息，并通过远动系统上传调度中心，确保数字化变电站更加安全、稳定的运行。","重庆大学;云南电网公司昆明供电局","2010.03.10#公开;2010.04.28#实质审查的生效;2011.04.13#授权","CN200910190888.9","G01R31\u002F00;G01R31\u002F02;G06F17\u002F14","熊小伏;唐广学;于军;胡之荣;陈星田;王燕祥;张羿",[],[],{"resultType":1085,"id":1222,"title":1223,"abstract":1224,"orgName":1225,"province":1090,"date":1180,"trl":13,"transferMode":13,"keywords":13,"industry":13,"patentType":1092,"legalStatus":1226,"isOpenLicense":1094,"isRevitalized":1095,"techMaturity":13,"starRating":13,"licenseFeeText":13,"patentNo":1227,"ipc":1228,"inventors":1229,"tags":1230,"tagNames":1231},"gpi_00937","一种热剂量实时监控方法及其设备","本发明公开了一种热剂量实时监控方法及其设备，该监控方法包括如下步骤：1)确定热辐照靶区；2)对靶区进行热辐照，并实时测量靶区组织的温度；3)根据所测得的靶区组织实时的温度－时间数据，通过右下公式计算靶区组织实时的热剂量值；⑤将计算出的热剂量值与组织发生凝固性坏死所需要的阈值热剂量进行比较。一种热剂量实时监控设备，包括测温装置、热辐照装置以及热剂量判定装置。本发明可实时监控治疗对象的热剂量值，不会给治疗组织造成过度热辐照，更不会损害正常组织。","重庆医科大学","2009.12.16#公开;2010.02.10#实质审查的生效;2012.06.27#授权","CN200810099779.1","A61N7\u002F02;A61B18\u002F04;G01J5\u002F52;A61B5\u002F055;A61B8\u002F00;G06F19\u002F00","李发琪;樊华",[],[],{"resultType":1085,"id":1233,"title":1234,"abstract":1235,"orgName":1236,"province":1090,"date":1180,"trl":13,"transferMode":13,"keywords":13,"industry":13,"patentType":1092,"legalStatus":1237,"isOpenLicense":1094,"isRevitalized":1095,"techMaturity":13,"starRating":13,"licenseFeeText":13,"patentNo":1238,"ipc":1239,"inventors":1240,"tags":1241,"tagNames":1242},"gpi_01436","一种矿用救灾指挥系统","本发明公开了一种矿用救灾指挥系统，包括救援终端、井下基站、防爆计算机、地面基站和监控计算机，其中，救援终端由对讲耳机、摄像头、多参数传感器、网络视频服务器构成；所述救援终端由救护队员随身携带，所述救援终端采集现场的语音、视频和环境参数，并将三种数据混合调制后输出到井下基站；同时救援终端接收井下基站输出的语音、视频信号；所述井下基站和防爆计算机放置在井下指挥基地，所述井下基站接收救援终端输出的信号，从中解调出语音、视频和环境参数，发送到所述防爆计算机上实时显示视频、环境参数和语音对讲，井下基站将接收到的救援终端输出的信号转发到地面基站；非常适合我国煤矿救护队使用，具有极大的经济效益和社会效益。","煤炭科学研究总院重庆研究院","2010.08.25#公开;2010.10.13#实质审查的生效;2012.06.13#授权;2014.08.20#专利权人的姓名或者名称、地址的变更;2014.08.20#专利权人的姓名或者名称、地址的变更","CN201010136452.4","E21F17\u002F18;H04L29\u002F08;H04B7\u002F26;H04N7\u002F18;E21F11\u002F00","吴燕清;康厚清;张军;胡运兵;宋劲;郑万波;肖勇;何昭友;张少华;秦伟",[],[],{"resultType":1085,"id":1244,"title":1245,"abstract":1246,"orgName":1236,"province":1090,"date":1180,"trl":13,"transferMode":13,"keywords":13,"industry":13,"patentType":1092,"legalStatus":1247,"isOpenLicense":1094,"isRevitalized":1095,"techMaturity":13,"starRating":13,"licenseFeeText":13,"patentNo":1248,"ipc":1249,"inventors":1250,"tags":1251,"tagNames":1252},"gpi_01803","一种节能型矿用多媒体应急救援通信系统","本发明提供一种节能型矿用多媒体应急救援通信系统，核心设备为矿用多功能无线Mesh网关、矿用多功能无线Mesh路由器以及多媒体业务服务器，网关和路由器均设置有主控系统板和WiFi Mesh系统板，主控系统板上设置有主控制器，主控制器的电源控制端与WiFi Mesh系统电源输入选通模块连接，WiFi Mesh系统板上设置有子控制器和WiFi智能接入卡，其特征在于：网关主控制器上设置有网关节能控制系统，路由主控制器上设置有路由节能控制系统，网关节能控制系统与路由节能控制系统有机融合，实现了低功耗嵌入式子系统去控制高功耗WIFI系统工作状态和软、硬休眠机制相结合的节能控制方法，有效延长设备待机时间。","2011.01.12#公开;2011.03.09#实质审查的生效;2013.02.20#授权;2014.08.20#专利权人的姓名或者名称、地址的变更;2014.08.20#专利权人的姓名或者名称、地址的变更","CN201010167955.8","H04L29\u002F08;H04W84\u002F12;H04W84\u002F18;E21F17\u002F18;E21F11\u002F00","宋文;黄强;王飞;戴剑波;梁强",[],[],{"resultType":1085,"id":1254,"title":1255,"abstract":1256,"orgName":1257,"province":1090,"date":1180,"trl":13,"transferMode":13,"keywords":13,"industry":13,"patentType":1092,"legalStatus":1258,"isOpenLicense":1094,"isRevitalized":1095,"techMaturity":13,"starRating":13,"licenseFeeText":13,"patentNo":1259,"ipc":1260,"inventors":1261,"tags":1262,"tagNames":1263},"gpi_01702","乙型肝炎病毒核心抗原与热休克蛋白的复合物及其制备方法和应用","本发明公开了乙型肝炎病毒核心抗原与热休克蛋白的复合物及其制备方法和应用，该复合物由乙型肝炎病毒核心抗原与糖调蛋白170以非共价键结合而成，能够激活识别乙型肝炎病毒核心抗原的特异性CTL，诱导强有力的抗病毒免疫，且不需要任何佐剂，在同种间应用不受MHC的限制；该复合物的制备方法简单，可以用于制备乙型肝炎治疗性疫苗，在乙型肝炎免疫治疗领域有着良好的开发应用前景。","中国人民解放军第三军医大学","2010.12.15#公开;2011.02.02#实质审查的生效;2013.01.30#授权","CN200910251052.5","C07K19\u002F00;A61K39\u002F29;A61P1\u002F16;A61P31\u002F20","吴玉章;杨曌",[],[],{"resultType":1085,"id":1265,"title":1266,"abstract":1267,"orgName":1257,"province":1090,"date":1180,"trl":13,"transferMode":13,"keywords":13,"industry":13,"patentType":1092,"legalStatus":1268,"isOpenLicense":1094,"isRevitalized":1095,"techMaturity":13,"starRating":13,"licenseFeeText":13,"patentNo":1269,"ipc":1270,"inventors":1271,"tags":1272,"tagNames":1273},"gpi_00139","二十八烷醇在制备防治缺氧性肺动脉高压症药物中的应用","本发明涉及二十八烷醇在制备防治缺氧性肺动脉高压症药物中的应用，其特征在于：将提取的纯度在98％以上的二十八烷醇与崩解剂－羧甲基淀粉混合，装入胶囊。每粒胶囊中含二十八烷醇10mg、羧甲基淀粉0.3mg。本发明可有效防治缺氧性肺动脉高压，可有效防治缺氧引起的肺血管结构改建，具有防治高原心脏病和肺源性心脏病的作用。","2008.03.12#公开;2010.10.13#授权","CN200710092800.0","A61K31\u002F045;A61K9\u002F48;A61P9\u002F12","高文祥;高钰琪;刘福玉;陈建;罗勇军;廖卫公",[],[],{"resultType":1085,"id":1275,"title":1276,"abstract":1277,"orgName":1257,"province":1090,"date":1180,"trl":13,"transferMode":13,"keywords":13,"industry":13,"patentType":1092,"legalStatus":1278,"isOpenLicense":1094,"isRevitalized":1095,"techMaturity":13,"starRating":13,"licenseFeeText":13,"patentNo":1279,"ipc":1280,"inventors":1281,"tags":1282,"tagNames":1283},"gpi_00282","二十八烷醇在制备防治高原红细胞增多症药物中的应用","本发明涉及二十八烷醇在制备防治高原红细胞增多症药物中的应用，其特征在于：将提取的纯度在98％以上的二十八烷醇与崩解剂—羧甲基淀粉混合，装入胶囊，每粒胶囊中含二十八烷醇10mg、崩解剂0.3mg。本发明有益的效果：可有效防治长期慢性缺氧所致红细胞增多；可有效提高机体缺氧耐受性；具有改善微循环的作用。","2008.08.20#公开;2008.10.15#实质审查的生效;2010.09.08#授权","CN200810069455.3","A61K31\u002F045;A61K9\u002F48;A61P43\u002F00;A61P9\u002F10","高文祥;高钰琪;刘福玉;廖卫公;周其全;蒋春华",[],[],{"resultType":1085,"id":1285,"title":1286,"abstract":1287,"orgName":1257,"province":1090,"date":1180,"trl":13,"transferMode":13,"keywords":13,"industry":13,"patentType":1092,"legalStatus":1288,"isOpenLicense":1094,"isRevitalized":1095,"techMaturity":13,"starRating":13,"licenseFeeText":13,"patentNo":1289,"ipc":1290,"inventors":1291,"tags":1292,"tagNames":1293},"gpi_01157","人α-防御素5抗病毒活性突变体多肽及制备方法和应用","本发明涉及一种人α-防御素5(HD5)抗病毒活性突变体多肽及制备方法和应用，所述突变体多肽的氨基酸序列的HD5中第21位谷氨酸被替换为精氨酸(E21R)。所述突变体多肽的制备方法，有固相化学合成法和基因工程制备法两种。本发明的HD5突变体多肽在有无血清存在的情况下均具有高效的抗病毒活性，其抗病毒作用较母本HD5多肽显著提高。本发明的HD5突变体多肽可以用于防治HSV、HPV及HIV等病毒的感染。","2010.05.12#公开;2010.06.30#实质审查的生效;2012.03.21#授权","CN200910191485.6","C07K14\u002F435;C07K1\u002F04;C12N15\u002F12;C12N15\u002F63;C12P21\u002F02;A61K38\u002F17;A61P31\u002F18;A61P31\u002F20;A61P31\u002F22;C12R1\u002F19;C12R1\u002F84","王军平;陈芳;王艾平;申明强;王崧;粟永萍;程天民",[],[],{"resultType":1085,"id":1295,"title":1296,"abstract":1297,"orgName":1257,"province":1090,"date":1180,"trl":13,"transferMode":13,"keywords":13,"industry":13,"patentType":1092,"legalStatus":1298,"isOpenLicense":1094,"isRevitalized":1095,"techMaturity":13,"starRating":13,"licenseFeeText":13,"patentNo":1299,"ipc":1300,"inventors":1301,"tags":1302,"tagNames":1303},"gpi_00489","人转录共激活因子PC4在制备诊断、治疗或预防肿瘤的制剂中的应用","本发明涉及人转录共激活因子PC4在制备诊断、治疗或预防肿瘤的制剂中的应用，具体地，所述诊断、治疗或预防肿瘤的制剂为诊断、治疗或预防肿瘤复发和转移的制剂或诊断、治疗或预防干细胞恶性转化的制剂，本发明所述诊断、治疗或预防肿瘤的制剂包括诊断、治疗或预防前列腺癌、乳腺癌或肺癌的制剂。本发明结果表明人转录共激活因子PC4基因在肺癌、乳腺癌、前列腺癌等多种人类肿瘤组织中均高表达，人转录共激活因子PC4基因可用于多种肿瘤的检测标志基因，特别是可作为晚期肿瘤骨转移肿瘤的预警的标志分子。","2009.03.04#公开;2009.04.29#实质审查的生效;2013.01.23#授权","CN200810070284.6","G01N33\u002F50;A61K38\u002F19;A61P35\u002F00;C12Q1\u002F68","史春梦;朱颖;粟永萍;程天民;张超;王少军;彭毅;冉新泽",[],[],{"resultType":1085,"id":1305,"title":1306,"abstract":1307,"orgName":1236,"province":1090,"date":1180,"trl":13,"transferMode":13,"keywords":13,"industry":13,"patentType":1092,"legalStatus":1308,"isOpenLicense":1094,"isRevitalized":1095,"techMaturity":13,"starRating":13,"licenseFeeText":13,"patentNo":1309,"ipc":1310,"inventors":1311,"tags":1312,"tagNames":1313},"gpi_01257","单总线双向通讯电路","本发明公开了一种单总线双向通讯电路，其特征在于：设置有控制电路，该控制电路的输出端连接有第一输入电路的下行口和接收电路的上行口；该控制电路由第二三极管、第三三极管和第五电阻组成，该第五电阻的一端为控制信号输入RTS端，第五电阻另一端接所述第三三极管的基极，该第三三极管的发射极接地，集电极接所述第二三极管的基极，该第二三极管的发射极接地，该第二三极管的集电极为所述控制电路的输出端。其显著效果是：具有单总线单\u002F双向通讯功能，能稳定可靠地进行远距离传输，功耗低，使用方便安全，无需隔离，抗干扰力强，误码率低，成本低廉。","2010.06.16#公开;2010.09.01#实质审查的生效;2012.11.14#授权;2014.08.20#专利权人的姓名或者名称、地址的变更;2014.08.20#专利权人的姓名或者名称、地址的变更","CN200910250865.2","H04L1\u0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","2009.10.07#公开;2009.12.02#实质审查的生效;2011.06.29#著录事项变更;2011.09.28#授权;2012.05.09#著录事项变更;2014.08.20#专利权人的姓名或者名称、地址的变更;2014.08.20#专利权人的姓名或者名称、地址的变更","CN200910103819.X","E21F17\u002F18;E21F5\u002F00;G08B31\u002F00","赵旭生;康建宁;刘程;李明建;崔俊飞;刁勇;韩文骥;杨义辉;唐韩英",[],[],{"resultType":1085,"id":1376,"title":1377,"abstract":1378,"orgName":1358,"province":1090,"date":1180,"trl":13,"transferMode":13,"keywords":13,"industry":13,"patentType":1092,"legalStatus":1379,"isOpenLicense":1094,"isRevitalized":1095,"techMaturity":13,"starRating":13,"licenseFeeText":13,"patentNo":1380,"ipc":1381,"inventors":1382,"tags":1383,"tagNames":1384},"gpi_00215","生石灰中游离氧化钙含量的测定方法","本发明提供了烟气脱硫领域中生石灰中游离氧化钙含量的测定方法，该方法利用乙酰乙酸乙酯和2－丁醇的混合液在煮沸回流冷凝的条件下，选择性的将生石灰中游离的氧化钙萃取出来，再通过过滤将生石灰中CaCO3等其它会消耗盐酸标准溶液的固体及生石灰中的不溶性残渣分离，再用盐酸对滤液中的氧化钙进行滴定分析，再计算得到生石灰中游离的氧化钙含量。该方法操作简单、测定准确、可靠、所用试剂少，为要求测定生石灰或熟石灰中游离氧化钙含量的干法烟气脱硫等工业领域提供了依据。","2008.06.18#公开;2008.08.13#实质审查的生效;2009.08.12#授权","CN200710093043.9","G01N21\u002F79;G06F19\u002F00","王方群;杜云贵;刘清才;李锋;隋建才;余宇;黄锐;周涛;赵培超;但康;王玉华;刘红辉;夏于红;冯治云",[],[],{"resultType":1085,"id":1386,"title":1387,"abstract":1388,"orgName":1389,"province":1090,"date":1180,"trl":13,"transferMode":13,"keywords":13,"industry":13,"patentType":1092,"legalStatus":1390,"isOpenLicense":1094,"isRevitalized":1095,"techMaturity":13,"starRating":13,"licenseFeeText":13,"patentNo":1391,"ipc":1392,"inventors":1393,"tags":1394,"tagNames":1395},"gpi_00346","电能计量装置错误接线模拟装置","本发明涉及一种电工培训用的接线装置，特别是一种用以对电力职工提升业务技能、技术练兵、竞赛鉴定、培训演示用的电能计量装置错误接线模拟装置，包括有电流错误接线模拟器、电压错误接线模拟器，电流错误接线模拟器、电压错误接线模拟器的三相电流、电压的输入端分别与外设虚拟负荷电源装置的三相虚拟电流、虚拟电压的输出端连接，电流错误接线模拟器、电压错误接线模拟器的三相电流、电压的输出端分别与外设电能计量装置的电流、电压的输入端连接。设置错误接线时只需拨动电流、电压错误接线模拟器的相应开关即可设置出：电流、电压的单一错误接线或组合错误接线，本发明结构简单、工作可靠、操作方便、效率高、可快速完成各种错误接线方式的改接。","重庆电力高级技工学校","2008.10.08#公开;2008.12.03#实质审查的生效;2011.05.18#授权","CN200710093251.9","G09B23\u002F18","青志明;夏冰;敬勇;吴彬;任小川;李杨",[],[],{"resultType":1085,"id":1397,"title":1398,"abstract":1399,"orgName":1236,"province":1090,"date":1180,"trl":13,"transferMode":13,"keywords":13,"industry":13,"patentType":1092,"legalStatus":1400,"isOpenLicense":1094,"isRevitalized":1095,"techMaturity":13,"starRating":13,"licenseFeeText":13,"patentNo":1401,"ipc":1402,"inventors":1403,"tags":1404,"tagNames":1405},"gpi_00750","矿用多功能无线数据收发与信号转换系统装置","本发明提供一种矿用多功能无线数据收发与信号转换系统装置，包括MCU单片机、看门狗电路、时钟晶振电路、本安直流电源转换电路，其特征在于：所述MCU单片机的输出端连接模拟和数字制式信号转换电路的输入端，并且所述模拟和数字制式信号转换电路提供连接外部监控分站的数字接口和模拟接口，接收MCU单片机输出的控制信号，输出模拟信号和数字频率制式信号；所述通信转换电路的控制端与MCU单片机的输出端连接；同时所述通信转换电路提供连接外部监控分站的通讯信号接口；本发明具有传输质量稳定、成本低、功耗低、抗干扰性强、使用方便安全、适用范围广的特点，非常适合我国煤矿等矿山行业使用。","2009.08.19#公开;2009.10.14#实质审查的生效;2012.10.03#授权;2014.08.20#专利权人的姓名或者名称、地址的变更;2014.08.20#专利权人的姓名或者名称、地址的变更","CN200910103364.1","H04B1\u002F38;H04L1\u002F00","宋文;黄强;鲁远祥;樊荣;汤朝明;郭江涛",[],[],49,30,{"list":1409,"total":1421,"page":100,"pageSize":100,"totalPages":1421},[1410],{"id":1411,"name":1412,"orgName":1413,"school":13,"gender":13,"title":13,"degree":13,"honor":1414,"position":1415,"researchDirection":1416,"intro":13,"province":13,"completeness":1417,"avatarAuthorized":1094,"sourceUrl":1418,"nameValid":1095,"tags":1419,"tagNames":1420},"cmv7rn1er000jddmmau8qulzd","应汉杰","苏州大学","ACADEMICIAN","苏州大学校长","生物制造与酶催化方向专家",80,"chaingraph:\u002F\u002F应汉杰",[],[],35346]