[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"chains-groupcat":3,"experts-list":4,"experts-coverage":102,"tags-groups":104},[],{"list":5,"total":99,"page":100,"pageSize":101,"totalPages":100},[6,47,68,84],{"id":7,"name":8,"orgName":9,"school":10,"gender":11,"title":12,"degree":13,"honor":13,"position":13,"researchDirection":14,"intro":15,"province":16,"completeness":17,"avatarAuthorized":18,"sourceUrl":19,"nameValid":20,"tags":21,"tagNames":46},"e5cb857f-19f2-4f6f-983e-279c78293537","吴静","西安交通大学生命科学与技术学院","西安交通大学","女","副教授",null,"近年来研究方向为生物化学和细胞生物学基础研究，主要从事肿瘤和衰老等疾病的发病机制、代谢调控和信号传导等基础研究，近；年所取得的研究成果已在 Cell 以及 Cell Metabolism 等国际一流杂志发表；余篇。主持国家自然科学基金面上项目、国家自然科学基金青年项目、教育部博士学科点新教工基金等资助项目，项目经费累计约 100 万元；Wu J , Liu J, Lapenta K, Desrouleaux R, Li MD, Yang X. Regulation of the urea cycle by CPS1 O-GlcNAcylation in response to dietary restriction and aging. J Mol Cell Biol. 2022；Lu X, Yang P, Zhao X, Jiang M, Hu S, Ouyang Y, Zeng L, Wu J . OGDH mediates the inhibition of SIRT5 on cell proliferation and migration of gastric cancer. Exp Cell Res. 2019；Lu X, Wu N, Yang W, Sun J, Yan K, Wu J . OGDH promotes the progression of gastric cancer by regulating mitochondrial bioenergetics and Wnt\u002Fβ-catenin signal pathway. OncoTargets and Therapy. 2019；Singh J.P., K. Zhang, J. Wu , X. Yang. O-GlcNAc signaling in cancer metabolism and epigenetics. Cancer Lett. 2015；Wu J , Damon B, Sadlonova A, Whisenhunt TR, Rustgi AK, Nie YZ, Paterson AJ, Yang X. O-GlcNAc Transferase Is Critical for TLE-Mediated Repression of Canonical Wnt Signaling. J Biol Chem. 2014；Zheng A, Li H, Wang X, Feng Z, Xu J, Cao K, Zhou B, Wu J* , Liu J. Anticancer Effect of a Curcumin Derivative B63；Zhang H, Wu J , Dong H, Khan SA, Chu ML, Tsuda T. Fibulin-2 Deficiency Attenuates Angiotensin II-Induced Cardiac Hypertrophy By Reducing Transforming Growth Factor- β Signaling. Clin Sci (Lond). 2014 (Co-first author；Ruan H.B., M.O. Dietrich, Z.W. Liu, M.D. Li, J.P. Singh, K. Qian, K. Zhang, M.R. Zimmer, J. Wu , T.L. Horvath, X. Yang. O-GlcNAc transferase-controlled AgRP neurons suppress browning of white fat. Cell. 2014；Ruan H.B., J.P. Singh, M.D. Li, J. Wu , X. Yang. Cracking the O-GlcNAc code in metabolism. Trends Endocrinol. Metab. 2013；Ruan HB, Han X, Li MD, Singh JP, Qian K, Azarhoush S, Zhao L, Bennett AM, Samuel VT, Wu J , Yates JR 3rd, Yang X. O-GlcNAc transferase\u002Fhost cell factor C1 complex regulates gluconeogenesis by modulating PGC-1 α stability. Cell Metab. 2012；Li MD, Ruan HB, Singh JP, Zhao L, Zhao T, Azarhoush S, Wu J , Evans RM, Yang X. O-GlcNAc transferase is involved in glucocorticoid receptor-mediated transrepression. J Biol Chem. 2012；Tsuda T, Wu J , Gao E, Joyce J, Markova D, Dong H, Liu Y, Zhang H, Zou Y, Gao F, Miller T, Koch W, Ma X, Chu ML. Loss of fibulin-2 protects against progressive ventricular dysfunction after myocardial infarction. J Mol Cell Cardiol. 2012；Zhang L, Park CH, Wu J , Kim H, Liu W, Fujita T, Balasubramani M, Schreiber EM, Wang XF, Wan Y. Proteolysis of Rad17 by Cdh1\u002FAPC regulates checkpoint termination and recovery from genotoxic stress. EMBO J. 2010；Wang L, Wu J , Cao H, Chen R, Zhang N, Fu J, Gao B, Zhang J, Hou R, Tang C, Ji Q. The Correlation Between Intestinal Gonadotropin-Releasing Hormone (GnRH) and Proglucagon in Hyperlipidemic Rats and Goto-Kakizaki (GK) Rats. Endocr Pathol. 2009 (co-first author；年-2021年 陕西省自然科学基金重点项目 “ O-GlcNAc糖基化修饰IDH2对结肠癌发生和代谢重塑的影响及分子机制研究 ”（S2019-JC-ZD-0074；年 -2018 年 国家自然科学基金面上项目“线粒体 O-GlcNAc 糖基化在衰老和卡路里限制过程中对线粒体代谢调控 ” （ 81471401 ），项目负责人；年 -2011 年 教育部高等学院博士学科点专项科研基金项目（新教工基金）“ Fibulin 2 调节心脏 EMT 重塑的分子机制研 究” （ 200806981054 ），项目负责人；年 -2006 年国家自然科基金青年项目“ NSAIDs 肿瘤预防途径的非 COX-2 依赖性 途径”（ NSFC No. 30300410 ），项目负责人","【产业方向】生物医药","陕西",64,false,"https:\u002F\u002Fgr.xjtu.edu.cn\u002Fjing_wu\u002Fzh_CN\u002Findex.htm",true,[22,25,28,31,34,37,40,43],{"code":23,"name":24},"CH-10","生物医药",{"code":26,"name":27},"CH-28","交通",{"code":29,"name":30},"CH-33","人工智能",{"code":32,"name":33},"GB-27","医药制造业",{"code":35,"name":36},"GB-67","资本市场服务",{"code":38,"name":39},"GB-73","研究和试验发展",{"code":41,"name":42},"GB-83","教育",{"code":44,"name":45},"SEI-04","生物产业",[24,27,30,33,36,39,42,45],{"id":48,"name":49,"orgName":50,"school":10,"gender":51,"title":52,"degree":13,"honor":13,"position":13,"researchDirection":53,"intro":54,"province":16,"completeness":55,"avatarAuthorized":18,"sourceUrl":56,"nameValid":20,"tags":57,"tagNames":67},"764813c5-71c0-4596-9707-9be9b2316358","刘鑫","西安交通大学公共卫生学院","男","教授","主持国家自然科学基金；项，含青年项目、面上项目、国家自然科学基金与英国皇家学会合作交流基金；主持营养亚洲研究基金，汤臣倍健营养科研基金，中国营养学会帝斯曼专项科研基金等，累计研究经费5；余万；Liu X , Bragg F, Yang L, Kartsonaki C, Guo, Du, H, Bian Z, Chen Y；Wang M, Xu K, Yang J, Bennett DA, Du H, Liu X * . Normal-weight obesity subtypes and 10-year risks of major vascular diseases in 0.3 million adults. Clin Nutr. 2024 Dec 27；Liu X, Lu L, Yao P, Ma Y, Wang F, Jin Q, Ye X, Hu F, Sun L, Lin X. Lipopolysaccharide binding protein, obesity status, and incidence of metabolic syndrome；Xu K, Zhang B, Liu Y, Mi B, Wang Y, Shen Y, Shi G, Dang S, Liu X * , Yan H . Staple Food Preference and Obesity Phenotypes；Liu X * , Lai H, Mi B, Qi X, Gan W, Du, H. Associations of Coarse Grain Intake with Undiagnosed Hypertension among Chinese Adults；Ma G, Li J, Xie J, Li Y, Xu K, He Y, Yang J, Du H, Liu X * . Pulse pressure and its association with body composition among Chinese men and women without diagnosed hypertension；Lai H, Li Y, He Y, Chen F, Mi B, Li J, Xie J, Ma G, Yang J, Xu K, Liao X, Yin Y, Liang J, Kong L, Wang X, Li Z, Shen Y, Dang S, Zhang L, Wu Q, Zeng L, Shi L, Zhang X * , Tian T * , Liu X * . Effects of dietary fibers or probiotics on functional constipation symptoms and roles of gut microbiota；Ma G, Li Y, He C, Li J, Xie J, Alballa MM, Xu K, Feng X, He J, Jia K, He Y, Li W, Chen F, Mi B, Yang J, Yu H, Liao X, Zhang B, Yang N, Dong Q, Wang Q * , Ze X * , Liu X * . Effects of Lactiplantibacillus plantarum on moderate dyslipidemia before medication involving gut microbiota and host genetics. NPJ Sci Food . 2026 Feb 9. doi；Li J, He Y, He J, Xie J, He C, Jia K, Wang M, Li W, Feng X, Ma G, Tang A, Xu K, Niu H, Liao X, Yu H, Shi L, Li L, Si L, Chen F, Mi B, Tian T * , Liu X * . Tailored effects of coarse grain substitution on blood pressure via gut microbiota-metabolite networks and host gene variants；He Y, Xu K, Li Y, Chang H, Liao X, Yu H, Tian T, Li C, Shen Y, Wu Q, Liu X * , Shi L. Metabolomic changes upon conjugated linoleic acid supplementation and predictions of body composition responsiveness. J Clin Endocrinol Metab . 2022 Aug 18；Jia K, She Y, He Y, He J, He Y, Xu K, Ma G, Li W, He C, Feng X, Wang M, Tang A, Sun X, Kong L * , Liu X * . Conjugated Linoleic Acid Supplementation Suppresses the De Novo Lipogenesis in Adults With High Body Fat；Chang H, Gan W, Liao X, Wei J, Lu M, Chen H, Wang S, Ma Y, Wu Q, Yu Y * , Liu X * . Conjugated linoleic acid supplements preserve muscle in high-body-fat adults；Liu X , Zhang G, Ye X, Li H, Chen X, Tang L, Feng Y, Shai I, Stampfer M, Hu F, Lin X. Effects of a low-carbohydrate diet on weight loss and cardiometabolic profile in Chinese women；Li S, Mi B, Qu P, Liu D, Lei F, Wang D, Zeng L, Kang Y, Shen Y, Zhu Z, Yan H, Liu X * , Dang S. Association of antenatal vitamin B complex supplementation with neonatal vitamin B12 status；Ma Y, Sun Y, Sun L, Liu X , Zeng R*, Lin X*, & Li Y*. Effects of gut microbiota and fatty acid metabolism on dyslipidemia following weight-loss diets in women；Wang M, Ma G, Li Y, Li J, Xie J, He J, He C, He Y, Jia K, Feng X, Tian T, Li H, Liao X * , Liu X * . Potential Modulatory Roles of Gut Microbiota and Metabolites in the Associations of Macronutrient-to-Physical Activity Ratios With Dyslipidemia. J Am Heart Assoc. 2025 May 20；Xu K, Shen Y, Shi L, Chen F, Zhang B, He Y, Wang Y, Liu Y, Shi G, Mi B, Zeng L, Dang S * , Liu X * , Yan H * . Lipidomic perturbations of normal-weight adiposity phenotypes and their mediations on diet-adiposity associations. Clin Nutr. 2024 Nov；Xu K, Zhang B, He Y, Wang Y, Liu Y, Shi G, Shen Y, Chen F, Mi B, Shi L, Zeng L, Liu X * , Dang S * , Yan H * . Serum Lipidomic Signatures Mediate the Association Between Coarse Grain Preference and Central Obesity in Adults With Normal Weight and High Wheat Intake. Mol Nutr Food Res. 2025 Jan；He J, He Y, Li J, Ma G, Li Y, Xie J, He C, Feng X, Jia K, Li W, Wang M, Tang A, Tian T, Liao X, Li W, Yan F, Zhang Y, Cao X, Zhang Y, Yang N, Liu X * , Wang Q * . Habitual coarse grain intake, gut microbiota, and hyperuricemia in individuals with or at risk of metabolic syndrome；Li W, Wang M, Xu K, He J, Feng X, Ma G, Li Y, Lai H, Tang A, He C, He Y, Jia K, Liao X, Yu H, Tian T, Liu X * . Coarse Grain Preference, Gut Microbiota Features, in Relation to Hypertriglyceridemia in Constipation Patients；Li J, Ma G, Xie J, Xu K, Lai H, Li Y, He Y, Yu H, Liao X, Wang X, Li Z, Kong L, Mi B, Shen Y, Tian T, Liu X * . Differential Gut Microbiota, Dietary Intakes in Constipation Patients with or without Hypertension. Mol Nutr Food Res . 2023 Sep 15；Yan T, Shi L * , Xu K, Bai J, Wen R, Liao X, Dai X, Wu Q, Zeng L, Peng W, Wang Y, Yan H, Dang S * , Liu X * , Habitual intakes of sugar-sweetened beverages associated with gut microbiota related metabolites and metabolic health outcomes in young Chinese adults, Nutrition, Metabolism and Cardiovascular Diseases, 2022 https；Xu, K, Shi, L, Zhang, B, Mi, B, Yang, J, Sun, X, Liao X, Dai X, Zeng L, Liu X * , Yan, H * . Distinct metabolite profiles of adiposity indices and their relationships with habitual diet in young adults. Nutrition, Metabolism and Cardiovascular Diseases . 2021, https；Liu X * , Shi L, Dai X * , Chen H, Zhang C, Wang P, Wu Q, Zeng L, Yan H, Plasma metabolites mediate the association of coarse grain intake with blood pressure in hypertension –free adults. Nutrition Metabolism and Cardiovascular Diseases . 2020 Aug；Liu X * , Wu D, Qi X, Niu Y, Li W, Lu Y, Chang J. The associations between carbohydrate and protein intakes with habitual sleep duration among adults living in urban and rural areas. Clinical Nutrition . 2018 Oct；Liu X * , Shi L, Sun L. Grain Intake and Cardiometabolic Health-Towards Precision Nutrition. Nutrients . 2023 Oct 30；Xie J, Li J, Ma G, Wang M, Li Y, He Y, Xu K, Tian T, Yang N, Wang Q, Chang J, Liu X * . Knowledge, Behavior, and Influencing Factors of Coarse Grain Consumption among Chinese Adults；Liu, X * , Chang, H, Lu, M, Chen, H, Wei, J, Liao, X. Take-away milk tea intake was associated with cholesterol independent of adiposity in young adults. Proceedings of the Nutrition Society , 2020, 79(OCE2). IF=7.0；Liu X * , Gan W, Gao C, Qi X, Liao X, Lin J, Zhao Y. The independent associations of protein consumption with body fat and glycaemic control in adult Chinese. European Journal of Nutrition. 2018 Jun 13. [Epub ahead of print]. IF=5.0；Liu X * , Liao X, Gan W, Ding X, Gao B, Wang H, Zhao X, Liu 5, Feng L, Abdulkadil W, Li Y. Inverse relationship between coarse food grain intake and blood pressure among young Chinese adults. American Journal of Hypertension . 2019 Mar 16；Liu X , Sun Q, Sun L, Liu G, Zong G, Lu L, Rosner B, Ye X, Li H, Lin X. The development and validation of new equations for estimating body fat percentage among Chinese men and women. British Journal of Nutrition . 2015 May；Liu X * , Zhao Y, Dang S, Li Q, Yan H. Equation - derived body fat percentage indicates metabolic abnormalities among normal ‐ weight adults in a rural Chinese population. American Journal of Human Biology . 2017 Jul 8；Liu X * , Liao X, Ren Q, Luo M, Yang L, Lin J, Chang J. Concerns regarding complementary feeding practices among urban Chinese mothers；Jebril M, Liu X *, Shi Z, Mazidi M, Altaher A, Wang Y *, Prevalence of Type 2 Diabetes and Its Association with Added Sugar Intake in Citizens and Refugees Aged 40 or Older in the Gaza Strip, Palestine. International Journal of Environmental Research and Public Health. 2020, 17(22), 8594；Jebril M, Mazidi M, Liu X , Baibing M, Arafat H, Shi Z, Wang Y. Association between war-related traumatic events and blood pressure trajectory；Han J, Liu X, Wang J, Tang M, Xu J, Tan S, Liu X * , Wu G*. Prognostic value of body composition in patients with digestive tract cancers；Yang X, Liu X , Tian G, Li H. Editorial；Yang J, Chang Q, Dang S, Liu X , Zeng L, Yan H. Dietary Quality during Pregnancy and Congenital Heart Defects. Nutrients . 2022；Li Z, Zhu G, Li C, Lai H, Liu X , Zhang L. Which Probiotic Is the Most Effective for Treating Acute Diarrhea in Children? A Bayesian Network Meta-Analysis of Randomized Controlled Trials. Nutrients . 2021；Liao X, Zhang Y, Xu B, Ali A, Liu X , Jia Q * . Inositol hexaphosphate sensitizes hepatocellular carcinoma to oxaliplatin relating inhibition of CCN2-LRP6-β-catenin-ABCG1 signaling pathway. Journal of Cancer. 2021；Schillemans T, Shi L, Liu X , Åkesson A, Landberg R, Brunius C. Visualization and Interpretation of Multivariate Associations with Disease Risk Markers and Disease Risk-The Triplot. Metabolites. 2019 Jul 6；Wei J, Liu X , Xue H, Wang Y, Shi Z. Comparisons of Visceral Adiposity Index, Body Shape Index, Body Mass Index and Waist Circumference and Their Associations with Diabetes Mellitus in Adults. Nutrients . 2019 Jul 12；Chang J, Liu X , Sun Y. Mortality due to acute myocardial infarction in China from 1987 to 2014；Fu Y, Liu X, Zhou B, Jiang A, Chai L. An updated review of worldwide levels of docosahexaenoic and arachidonic acid in human breast milk by region. Public Health Nutrition . 2016 Oct；Liu G, Sun L, Pan A, Zhu M, Li Z, Wang Z, Liu X , Ye X, Li H, Zheng H, Ong CN, Yin H, Lin X, Chen Y. Nickel exposure is associated with the prevalence of type 2 diabetes in Chinese adults. International Journal of Epidemiology . 2015 Feb；Sun L, Qi Q, Zong G, Ye X, Li H, Liu X , Zheng H, Hu FB, Liu Y, Lin X. Elevated plasma retinol-binding protein 4 is associated with increased risk of type 2 diabetes in middle-aged and elderly Chinese adults. Journal of Nutrition . 2014 May；Ye X, Zong G, Liu X , Liu G, Gan W, Zhu J, Lu L, Sun L, Li H, Hu FB, Lin X. Development of a new risk score for incident type 2 diabetes using updated diagnostic criteria in middle-aged and older Chinese. PLoS One. 2014 May 12；Liu G, Lu L, Sun Q, Ye X, Sun L, Liu X , Zong G, Jin Q, Li H, Lin X. Poor vitamin D status is prospectively associated with greater muscle mass loss in middle-aged and elderly Chinese. Journal of the Academy of Nutrition and Dietetics. 2014 Oct；Lei F, Liu D, Shen Y, Zhang L, Li S, Liu X , Shi G, Li J, Zhao Y, Kang Y, Dang S, Yan H. Study on the influence of pregnancy-induced hypertension on neonatal birth weight. J Investig Med. 2018 Apr 9. [Epub ahead of print] IF=2.6；Mi B, Wen X, Li S, Liu D, Lei F, Liu X , Wang D, Li X, Shittu AAT, Dang S, Yan H. Parameterization of the mid-trimester drop in blood pressure trajectory during pregnancy and its utility for predicting preeclampsia. J Hypertens . 2020 Jul；Mi B, Wen X, Li S, Liu D, Lei F, Liu R, Shen Y, Chen Y, Zeng L, Liu X, Dang S, Yan H. Vegetable dietary pattern associated with low risk of preeclampsia possibly through reducing proteinuria. Pregnancy Hypertens. 2019 Apr；Liu X * , Ren Q, Luo M, Li K. Before It’s Too Late to Check the Sugar in the Cup. EC Nutrition. 2016 Jan；Lin X, Liu X , Li H, Sun L, Huo S, Xiong Q, Niu Z, Luo Y. Dietary strategies in weight control (Chinese). Journal of Internal Medicine Concept & Practice . 2017(4；Li S, Lei F, Zhang R, Liu D, Qu P, Cheng Y, Liu X , Chen F, Dang S, Yan H. Socioeconomic disparity in the diet quality of pregnant women in Northwest China. Asia Pac J Clin Nutr 2019；Li S, Liu D, Zhang R, Lei F, Liu X , Cheng Y, Li C, Xiao M, Guo L, Li M, Zhang B, Zhu Z, Shi G, Liu Y, Dang S, Yan H. The association between maternal dietary folate intake and folic acid supplementation with small-for-gestational-age births；Jia P, Xue H, Liu S, Wang H, Yang L, Hesketh, Ma L, Cai H, Liu X , Wang Y, Wang Y. Opportunities and challenges of using big data for global health. Science Bulletin . 2019,64(22；Sun Y, Chang J, Liu X , Liu C. Mortality trends of liver diseases in mainland China over three decades；Zhang Y, Hou LS, Tang WW, Xu F, Xu RH, Liu X , Liu Y, Liu JX, Yi YJ, Hu TS, Hu R, Wang TD, Huang XB. High prevalence of obesity-related hypertension among adults aged 40 to 79 years in Southwest China. Sci Rep . 2019 Nov 1；Liang B, Tang WW, Zhang WQ, Huang C, Liu Y, Xu F, Liu X , Yuan N, Liu JX, Yi YJ, Xu RH, Hu D, Huang XB, Cao X. Prevalence and Associated Factors of Diabetes Mellitus in a Very Elderly Chinese Population；Yang J, Kang Y, Chang Q, Zhang B, Liu X, Zeng L, Yan H, and Dang S, Maternal Zinc, Copper, and Selenium Intakes during Pregnancy and Congenital Heart Defects. Nutrients, 2022.14(5), p.1055. IF=5.9；Li C, Liu Y, Shi G, Mi B, Zeng L, Li Q, Shen Y, Zhao Y, Pei L, Kang Y, Xiao S, Liu X , Dai J, Zhang Y, Wang X, Wang X, Wang D, Yan H, Dang S. Cohort Profile；Li Z, Zhu G, Li C, Lai H, Liu X , Zhang L. Which Probiotic Is the Most Effective for Treating Acute Diarrhea in Children? A Bayesian Network Meta-Analysis of Randomized Controlled Trials. Nutrients. 2021 Nov 29；Chang J, Zhu S, Zhang Y, Carvalho N, Xu S, Lu Y, Liu X , Fang Y, Meng Q. Determinants of parental demand of human papillomavirus vaccination for adolescent daughters in China；Li X, Yang J, Zhou X, Dai C, Kong M, Xie L, Liu C, Liu Y, Li D, Ma X, Dai Y, Sun Y, Jian Z, Guo X, Lin X, Li Y, Sun L, Liu X , Jin L, Tang H, Zheng Y, Hong S. Ketogenic diet-induced bile acids protect against obesity through reduced calorie absorption. Nat Metab. 2024 Jul；林旭、刘鑫、孙亮；改善功能性便秘——膳食纤维和益生菌齐联手；面食为主的群体中，偏爱杂粮与体重正常的中心肥胖负相关；刘鑫课题组在正常体重肥胖亚型与 10 年心血管发病风险研究中取得突破；刘鑫课题组在膳食、肠道菌、肥胖及高血压研究中取得系列进展 https；生命时报；JCEM；人类营养与代谢实验室在肥胖表型脂质谱研究中取得新进展 http；刘鑫课题组在中国人群杂粮摄入、血浆代谢谱及高血压风险研究中取得系列进展 https；Lancet Public Health 刊登公共卫生学院青年教师关于吸烟与糖尿病的研究成果 https；刘鑫课题组在共轭亚油酸改善体成分研究中取得进展 http；Newtrition® 亚洲研究基金获得者通过全新临床研究推动亚洲地区紧迫健康问题的解决 https","【产业方向】大健康",59,"https:\u002F\u002Fgr.xjtu.edu.cn\u002Fxinliu\u002Fzh_CN\u002Findex.htm",[58,59,60,61,64],{"code":26,"name":27},{"code":35,"name":36},{"code":38,"name":39},{"code":62,"name":63},"GB-84","卫生",{"code":65,"name":66},"GB-95","群众团体、社会团体和其他成员组织",[27,36,39,63,66],{"id":69,"name":70,"orgName":71,"school":10,"gender":11,"title":72,"degree":13,"honor":13,"position":13,"researchDirection":73,"intro":54,"province":16,"completeness":55,"avatarAuthorized":18,"sourceUrl":74,"nameValid":20,"tags":75,"tagNames":83},"eec0e396-a468-4771-ae8a-0712cf165175","孙月","西安交通大学护理学系","讲师","孙月，博士，助理教授。2024年7月毕业于北京大学，获医学博士学位。2024年入选西安交通大学“青年优秀人才支持计划”A类。；主持中国博士后科学基金面上项目、陕西省人社厅项目、北京大学“未名护理”领军人才科研创新基金重点项目等； 作为核心骨干参与国家社会科学基金重大项目、国家自然科学基金面上项目等科研课题 。以第一作者发表SCI论文16篇（JCR Q1区 10篇）， 包括Age and Ageing、Metabolism、International Journal of Nursing Studies等领域Top期刊，入选Web of Science高被引论文 。申请国家授权发明专利两项，参编北京大学研究生规划教材、人卫标准临床专科知识库等 论著4部。担任INR英文期刊青年编委以及International Journal of Nursing Studies、JMIR等领域权威期刊审稿人，获授权国家发明专利2项。 曾荣获北京大学优秀毕业生、北京大学博士研究生校长奖学金、北京大学学术创新奖等。；研究方向 ：老年健康管理、循证护理与智能决策。","https:\u002F\u002Fgr.xjtu.edu.cn\u002Fsun.yue\u002Fzh_CN\u002Findex.htm",[76,77,78,79,82],{"code":26,"name":27},{"code":35,"name":36},{"code":38,"name":39},{"code":80,"name":81},"GB-74","专业技术服务业",{"code":62,"name":63},[27,36,39,81,63],{"id":85,"name":86,"orgName":87,"school":10,"gender":13,"title":52,"degree":13,"honor":13,"position":13,"researchDirection":88,"intro":15,"province":16,"completeness":55,"avatarAuthorized":18,"sourceUrl":89,"nameValid":20,"tags":90,"tagNames":98},"2a5c293c-1fd8-4263-a3d8-85bca9bdc0d9","李冬民","西安交通大学基础医学院","（1）肥胖、非酒精性脂肪肝等代谢性疾病的发病机制及靶向治疗；；（2）糖脂代谢的表观遗传调控；；（3）肠道菌群、免疫代谢与非酒精性脂肪肝病。；代表性论文（ # 共同第一作者； * 通讯作者）：；Lu K#, He L#, Guo Z#, Li M, Cheng X, Liu S, Zhang T, Chen Q, Zhao R, Yang L, Wu X, Cheng K, Cao P, Wu L, Shahzad M, Zheng M, Jiao L, Wu Y, and Dongmin Li* . PDCD4 deficiency in hepatocytes exacerbates nonalcoholic steatohepatitis through enhanced MHC class II transactivator expression. Metabolism. 2024 Sep 27;161:156036. doi: 10.1016\u002Fj.metabol.2024.156036 （ SCI, IF= 10.8; JCR=Q1)；Zhao R#, Guo Z#, Lu K, Chen Q, Riaz F, Zhou Y, Yang L, Cheng X, Wu L, Cheng K, Feng L, Liu S, Wu X, Zheng M, Yin C, Dongmin Li*. Hepatocyte-specific NR5A2 deficiency induces pyroptosis and exacerbates non-alcoholic steatohepatitis by downregulating ALDH1B1 expression. Cell Death Dis. 2024 Oct 23;15(10):770. doi: 10.1038\u002Fs41419-024-07151-1. （ SCI, IF=8.1; JCR=Q1)；Lin Cao, Yue Zhou, Shuai Lin, Chunyan Yang, Zixuan Guan, Xiaofan Li, Shujie Yang, Tong Gao, Jiazhen Zhao, Ning Fan, Yanan Song, Dongmin Li , Xiang Li, Zhuo Li, Feng Guan*, and Zengqi Tan*. The trajectory of vesicular proteomic signatures from HBV-HCC by chitosan-magnetic bead-based separation and DIA-proteomic analysis. J Extracell Vesicles. 2024 Sep;13(9):e12499. doi: 10.1002\u002Fjev2.12499 （ SCI, IF=15.5; JCR=Q1)；Lu K, Cheng X, He L, Li M, Chen Q, Qian C, Zhao R, Yang L, Liu F, Liu S, Zhang T, Feng L, Wu L, Wu X, Xu N, Li Y, Wang J, Han Y, Yuan H, Liu T*, Zheng M*, Lu S*, Li D*. LNCHC directly binds and regulates YBX1 stability to ameliorate metabolic dysfunction-associated steatotic liver disease progression. Liver Int. 2024 Jun 7. doi: 10.1111\u002Fliv.15975. Epub ahead of print. PMID: 38847599. （ SCI, IF= 6.0; JCR=Q1)；Lu K#, Zhou Y#, He L, Li Y, Shahzad M, Li D*. Coprococcus protects against high-fat diet-induced nonalcoholic fatty liver disease in mice. J Appl Microbiol. 2024 Jun 3;135(6):lxae125. doi: 10.1093\u002Fjambio\u002Flxae125. PMID: 38830802. （ SCI, IF= 3.2; JCR=Q2)；Lina Feng, Farooq Riaz, Kaikai Lu, Xiaona Cheng, Yanping Chen , Rong Zhao, Litao Wu, Shemin Lu and Dongmin Li* . Leucine Aminopeptidase 3:a Promising Serum Biomarker Candidate for Nonalcoholic Steatohepatitis Diagnosis. Int Immunopharmacol. 2023 Apr 12;119:110152. doi: 10.1016\u002Fj.intimp.2023.110152. （ SCI, IF= 5.714; JCR= Q1)；Zhong Y, Xiao Y, Gao J, Zheng Z, Zhang Z, Yao L*, Li D*. Curcumin improves insulin sensitivity in high-fat diet-fed mice through gut microbiota. Nutr Metab (Lond). 2022 Nov 8;19(1):76. doi: 10.1186\u002Fs12986-022-00712-1. PMID: 36348361. （ Published ： 08 November 2022 ）（ SCI, IF= 4.127; JCR=Q3)；Qian Chen#, Jing Yi#, Fangtong Liu, Jing Li, Kaikai Lu, Xuan Wang, Fujun Zhang, Ya Li, Litao Wu, Xudong Yang, Shemin Lu and Dongmin Li*. TGF-β1 contributes to the hepatic inflammation in animal models with nonalcoholic steatohepatitis by Smad3\u002FTLR2 signaling pathway. Mol Immunol. 2022 Dec;152:129-139. doi: 10.1016\u002Fj.molimm.2022.10.014. Epub 2022 Nov 2. （ SCI, IF= 4.363; JCR=Q3)；Jun Wang, Xinrong Sun, Lianying Jiao, Zhengtao Xiao,Farooq Riaz, Yufeng Zhang, Pengfei Xu, Ruiqing Liu,Tiantian Tang, Meiqi Liu and Dongmin Li*. Clinical Characteristics and Variant Analyses of Transient Infantile Hypertriglyceridemia Related to GPD1 gene. Front Genet. 2022 Aug 16;13:916672. （ SCI, IF=4.772; JCR= Q1 ）；Lina Feng#, Yanping Chen#, Ke Xu, Yingchao Li, Farooq Riaz, Kaikai Lu, Qian Chen, Xiaojuan Du, Litao Wu, Dan Cao, Chunyan Li, Shemin Lu, Dongmin Li* . Cholesterol-induced leucine aminopeptidase 3 (LAP3) upregulation inhibits cell autophagy in pathogenesis of NAFLD. Aging (Albany NY). 2022 Apr 11;14(7):3259-3275. （ SCI, IF= 5.955; JCR=Q1)；Zeyu Dong, Fangzhou He, Xiaosong Yan, Yuanming Xing, Yuyang Lei, Jie Gao, Ming He, Dongmin Li , Liang Bai, Zuyi Yuan, John Y-J. Shyy. Hepatic Reduction in Cholesterol 25-Hydroxylase Aggravates Diet-induced Steatosis. Cellular and Molecular Gastroenterology and Hepatology. 2022 Jan 3, 13(4):1161-1179. （ SCI, IF= 9.225, JCR=Q1)；Farooq Riaz, Qian Chen, Kaikai Lu, Ezra Kombo Osoro, Litao Wu, Lina Feng, Rong Zhao, Luyun Yang, Yimeng Zhou, Yingli He, Li Zhu, Xiaojuan Du, Muhammad Sadiq, Xudong Yang and Dongmin Li *. Inhibition of miR-188-5p alleviates Hepatic Fibrosis by significantly reducing the activation and proliferation of HSCs through PTEN\u002FPI3K\u002FAKT pathway. Journal of Cellular and Molecular Medicine(JCMM), 2021, doi.org\u002F10.1111\u002Fjcmm.16376 （ SCI, IF= 5.310; JCR=Q2)；Jing Li#, Qian Chen#, Jing Yi, Xi Lan, Kaikai Lu, Xiaojuan Du, Zizhen Guo, Yuanxu Guo, Manman Geng, Dongmin Li *and Shemin Lu*. IFN-γ Contributes to the Hepatic Inflammation in HFD-Induced Nonalcoholic Steatohepatitis by STAT1β\u002FTLR2 Signaling Pathway. Mol Immunol. 2021Jun; 134:118-128. （ SCI, IF= 4.407; JCR=Q3)；Kaikai Lu, Qian Chen, Mengda Li ， Lei He ， Farooq Riaz ， Tianyun Zhang and Dongmin Li* . Programmed Cell Death Factor 4 (PDCD4), a Novel Therapy Target for Metabolic Diseases besides Cancer. Free Radic Biol Med. 2020 Nov 1;159:150-163. （ SCI, IF=7.376; JCR=Q1 )；Kaiting Ning#, Kaikai Lu#, Qian Chen, Zizhen Guo, Xiaojuan Du, Farooq Riaz, Lina Feng, Yuping Fu, Chunyan Yin, Fujun Zhang, Litao Wu and Dongmin Li *. Epigallocatechin Gallate Protects Mice against Methionine-Choline-Deficient-Diet induced Non-alcoholic Steatohepatitis by Improving Gut Microbiota to Attenuate Hepatic Injury and Regulate Metabolism. ACS Omega 2020, 5, 33, 20800–20809 （ SCI, IF= 3.512; JCR=Q2)；Litao Wu, Juan Sun, Li Liu, Xiaojuan Du, Yan Liu, Xiaofei Yan, Ezra Kombo Osoro, Fujun Zhang, Lina Feng, Dong Liang, Yazhao Li, Qian Chen, Sha Sun, Lei Zhang, Xi Lan*, Dongmin Li* and Shemin Lu. Anti-toll-like receptor 2 antibody ameliorates hepatic injury, inflammation, fibrosis and steatosis in obesity-related metabolic disorder rats via regulating MAPK and NF-κB pathways. 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Mol Cell Endocrinol. 2013; 374(1-2): 35-45. (SCI, IF=4.405; JCR=Q2)；Dongmin Li #, Xuan Wang#, Wuchao Ren, Juan Ren, Xi Lan, Feimiao Wang, Hongmin Li, Fujun Zhang, Yan Han, Tianbao Song, Rikard Holmdahl, Shemin Lu, High expression of liver histone deacetylase 3 contributes to high-fat-diet-induced metabolic syndrome by suppressing the PPAR-γ and LXR-α-pathways in E3 rats ［ J ］ . Mol Cell Endocrinol. 2011; 344(1-2):69-80. (SCI, IF=4.405; JCR=Q2)；Jie Ma#, Dong-Min Li #, Rui Zhang, Xu-Dong Yang, Cheng-Ge Gao, She-Min Lu, Sheng-Nan Wu, and Lei Wang. Genetic analysis of glutamate cysteine ligase modifier (GCLM) gene and schizophrenia in Han Chinese ［ J ］ Schizophr Res. 2010 Jun;119(1-3):273-4. （ SCI, IF: 4.458; JCR=Q1)；Dongmin Li, Wuchao Ren, Xuan Wang, Feimiao Wang, Yu Gao, Qilan Ning, Yan Han, Tianbao Song, Shemin Lu. A Modified Method using TRIzol® Reagent and Liquid Nitrogen Produces High-Quality RNA from Rat Pancreas ［ J ］ . Appl Biochem Biotechnol, 2009 ， 158:253-261 （ SCI, IF= 3.1 ; JCR=Q2 )","https:\u002F\u002Fgr.xjtu.edu.cn\u002Flidongm\u002Fzh_CN\u002Findex.htm",[91,92,93,96,97],{"code":23,"name":24},{"code":26,"name":27},{"code":94,"name":95},"FU-07","元宇宙",{"code":32,"name":33},{"code":44,"name":45},[24,27,95,33,45],4,1,30,{"schools":103},297,[]]